Current Issue : July-September Volume : 2015 Issue Number : 3 Articles : 1 Articles
Solid dispersions have been known to be one amongst the recent means of improving the dissolution rate by enhancement of solubility and hence the bioavailability of poorly water soluble drugs. Solid dispersion nothing to the “The dispersion of one or more active ingredients in an inert carrier or matrix, where the active ingredients could exist in finely crystalline, solubilized or amorphous state ” Several water soluble carriers such as methyl cellulose, urea, lactose, citric acid, polyvinyl pyrolidone and polyethylene glycols 4000 and 6000 are used as carriers for solid dispersion. Thus the solid dispersion technique can be successfully used for the improvement of dissolution of Cinnarizine antihistamic category drug which has great need for antiemetic properties. Polyethyl Glycol 6000 has been used for the preparation of solid dispersion as a component of the binary system for various drugs Cinnarizine. And therefore solid dispersion is one amongst such techniques is the formulation of solid dispersion for the solubility enhancement....
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